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Effects of molecular hydrogen supplementation on fatigue and aerobic capacity in healthy adults: A systematic review and meta-analysis

The study aimed to investigate the effects of hydrogen (H2) supplementation on fatigue and aerobic capacity in healthy adults during high-intensity exercise.

Fatigue during exercise can affect performance and increase the risk of injury. Finding safe and effective strategies to reduce fatigue and enhance aerobic capacity is crucial for both athletes and non-athletes.

The researchers conducted a systematic review and meta-analysis of studies investigating the effects of H2 supplementation on fatigue and aerobic capacity. They searched databases for relevant studies and analyzed the data to determine the overall impact of H2 supplementation.

The study found that H2 supplementation can effectively reduce subjective fatigue and blood lactate levels after high-intensity exercise. However, it did not significantly improve aerobic capacity.

Factors such as participant training status, the timing and duration of H2 intake, and the type of exercise performed can influence the effectiveness of H2 supplementation on fatigue.

H2 may act as a neuroprotective agent, reducing oxidative stress and inflammation, and modulating exercise-induced acidosis. However, further research is needed to fully understand these mechanisms.

The findings suggest that H2 supplementation could be a useful strategy for reducing fatigue, particularly in untrained individuals, but may not significantly enhance aerobic capacity. Future research should address the limitations and explore optimal protocols for H2 supplementation in different populations.

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