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The study aimed to investigate the effectiveness of hydrogen-enriched water (HW) in eliminating fine particles from the lungs and blood, as well as its ability to protect against lung injuries caused by these particles.
Rats and mice were given HW or purified water (PW) for a certain period.
Carbon nanoparticles (CNP) were introduced into the rats’ lungs, while carbon microparticles (CMP) were injected into the mice’s bloodstream.
Various parameters, including body weights, blood samples, lung tissue, and phagocytic activity, were analyzed to assess the effects of HW.
HW significantly reduced the accumulation of CNP in the lungs and blood, as well as inflammatory lesions.
It enhanced the clearance of CNP from the lungs and CMP from the bloodstream by increasing phagocytic activity.
HW also attenuated lung injuries caused by CNP exposure by inhibiting lipid peroxidation.
The findings suggest that HW could be a promising intervention for reducing the body burden of fine particles and protecting against lung damage caused by air pollution.
HW’s antioxidative and anti-inflammatory properties make it a potential candidate for mitigating the adverse health effects of particulate matters.
