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Molecular hydrogen therapy for neurological diseases, a review of current evidence

Hydrogen therapy involves the use of molecular hydrogen to treat various neurological diseases. It works by selectively scavenging harmful free radicals in the body, reducing oxidative stress, inflammation, and cellular damage.

Hydrogen therapy shows potential in treating conditions such as stroke, mild dementia, multiple sclerosis, neurotrauma (such as traumatic brain injury), and global brain injury (such as asphyxia-induced cardiac arrest).

In stroke, hydrogen therapy can reduce reperfusion injury (injury caused when oxygen returns to the brain) by scavenging free radicals, protecting the blood-brain barrier, and decreasing cerebral edema (swelling on the brain). It may also improve clinical outcomes and reduce infarct size in patients (size of blockage in the blood vessels).

Hydrogen therapy has shown promising results in animal models of Alzheimer’s disease by reducing oxidative stress, inflammation, and neuronal damage. Human studies have demonstrated improvements in cognitive function and symptom management with the help of hydrogen therapy.

In neurotrauma, hydrogen therapy has been shown to protect the blood-brain barrier, decrease cerebral edema (swelling of the brain), and inhibit oxidative stress and inflammation. This may lead to improved neurobehavioral outcomes and survival rates in animal models.

Human studies have shown no serious adverse effects related to hydrogen therapy administration. It appears to have a good safety profile across various neurological conditions.

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